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Ketamine is the main substance, the design of analogues was taken from it. We have a separate article about K and trip reports once and twice. Ketamine hydrochloride (“Ketamine”) is widely used for medical purposes all over the world. This drug is widely used in veterinary practice, during various types of surgical interventions. The abilityRead More

4-methylaminorex is a chemical compound derived from aminorex. It has a structural similarity with amphetamines. It produces a psychostimulating effect and is used as a drug. It can cause a dangerous irreversible complication — pulmonary hypertension. Isomers 4-methylaminorex can exist in the form of four isomers: cis-4R,5S, cis-4S,5R, trans-4S,5S, trans-4R,5R. Mechanism of action 4-methylaminorex increasesRead More

Dissociative drugs belong to the class of anesthetics, which are also called “dissociative anesthetics”, since initially the purpose of their elimination was exclusively medical. The meaning of the name of drugs “dissociatives” is that these drugs disrupt and unbalance the elements of the mind, break the connections between neuroreceptors. Memory, perception, consciousness and motor activityRead More

Description of the active substance Diazepam. Formula: C16H13ClN2O, chemical name: 7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepine-2-one. Pharmacological group: neurotropic agents, antiepileptic agents; agents affecting neuromuscular transmission; anxiolytics, benzodiazepine derivative. Pharmacological action: anticonvulsant, anxiolytic, central muscle relaxant, sedative, hypnotic. Pharmacological properties Diazepam acts on specific benzodiazepine receptors, which are located in postsynaptic GABA-receptor complexes in the thalamus, limbic system, hypothalamus, insertionRead More

LSD is a semi-synthetic psychoactive substance from the tryptamine family. LSD can be considered the most famous psychedelic, used or used as a recreational drug, an entheogen, as well as as a tool in various transcendental practices such as meditation, psychonautics, or illegal (but legal in the past) psychedelic psychotherapy. LSD is synthesized from lysergicRead More

MDA (3,4-methylenedioxy-amphetamine) The structure of MDA can be considered as an aromatic ring (3,4-methylenedioxy-phenyl ring) with a three-carbon chain extending from it. The amino group is located on the second of the three carbon atoms. Isomers in which the amino group is shifted to the first of the carbon atoms (benzylamine) or to the thirdRead More

A number of benzimidazole opioids have been developed , the most famous of which is the highly effective, but never commercially available, etonitazene . The structure-activity relationship has been investigated to a reasonable extent. The optimal substitution pattern is quite clearly defined (for example, N, N-diethyl on amine nitrogen, 4-ethoxy on the benzyl ring andRead More

Pharmacological properties Benzodiazepines work in the body by increasing the amount of gamma-aminobutyric acid in the brain and reducing neuronal excitability. This reduces the interaction between neurons, which manifests itself in a calming effect on many brain functions. Some of the drugs are half removed from the body within half a day, while others haveRead More

The substance consists of eighteen carbon atoms, twenty-one hydrogen atoms, one nitrogen atom, and four oxygen atoms (C18H21NO4). Nomenclature Tilox, Oxi 80, OxyContin, Percotset, Oxicotton, Percodon, Roxicodon, Roxitset. Name according to IUPAC: (5R,9R,13S,14S)-14-гидрокси-3-метокси-17-метил-4,5-epoxymorphinan-6-он. Form of production Intramuscular injections, medication in the form of capsules, tablets, solution for intravenous manipulation. History of the substance The firstRead More

Description of the drug tramadol, is it a narcotic substance or is it safer as a medical perparate? Is there an opioid dependence on tramadol? What is the opioid potency of the drug tramadol? We will try to present all these answers in this article. Tramadol is a drug that is sold in a pharmacyRead More